Effect of Exercise on Motor and Nonmotor Symptoms of Parkinson's Disease
Identifieur interne : 000029 ( Main/Exploration ); précédent : 000028; suivant : 000030Effect of Exercise on Motor and Nonmotor Symptoms of Parkinson's Disease
Auteurs : Khashayar Dashtipour [États-Unis] ; Eric Johnson [États-Unis] ; Camellia Kani [États-Unis] ; Kayvan Kani [États-Unis] ; Ehsan Hadi [États-Unis] ; Mark Ghamsary [États-Unis] ; Shant Pezeshkian [États-Unis] ; Jack J. Chen [États-Unis]Source :
- Parkinson's Disease [ 2090-8083 ] ; 2015.
Abstract
Url:
DOI: 10.1155/2015/586378
PubMed: 25722915
PubMed Central: 4333331
Affiliations:
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Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of Exercise on Motor and Nonmotor Symptoms of Parkinson's Disease</title>
<author><name sortKey="Dashtipour, Khashayar" sort="Dashtipour, Khashayar" uniqKey="Dashtipour K" first="Khashayar" last="Dashtipour">Khashayar Dashtipour</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
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</author>
<author><name sortKey="Johnson, Eric" sort="Johnson, Eric" uniqKey="Johnson E" first="Eric" last="Johnson">Eric Johnson</name>
<affiliation wicri:level="2"><nlm:aff id="I2">Department of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
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<author><name sortKey="Kani, Camellia" sort="Kani, Camellia" uniqKey="Kani C" first="Camellia" last="Kani">Camellia Kani</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
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<author><name sortKey="Kani, Kayvan" sort="Kani, Kayvan" uniqKey="Kani K" first="Kayvan" last="Kani">Kayvan Kani</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hadi, Ehsan" sort="Hadi, Ehsan" uniqKey="Hadi E" first="Ehsan" last="Hadi">Ehsan Hadi</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ghamsary, Mark" sort="Ghamsary, Mark" uniqKey="Ghamsary M" first="Mark" last="Ghamsary">Mark Ghamsary</name>
<affiliation wicri:level="2"><nlm:aff id="I3">Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
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<author><name sortKey="Pezeshkian, Shant" sort="Pezeshkian, Shant" uniqKey="Pezeshkian S" first="Shant" last="Pezeshkian">Shant Pezeshkian</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
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</author>
<author><name sortKey="Chen, Jack J" sort="Chen, Jack J" uniqKey="Chen J" first="Jack J." last="Chen">Jack J. Chen</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, School of Medicine, Loma Linda University, Loma Linda, CA 92354</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="I4">Department of Pharmacy Practice, College of Pharmacy, Marshal B. Ketchum University, Fullerton, CA 92831, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pharmacy Practice, College of Pharmacy, Marshal B. Ketchum University, Fullerton, CA 92831</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
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<series><title level="j">Parkinson's Disease</title>
<idno type="ISSN">2090-8083</idno>
<idno type="eISSN">2042-0080</idno>
<imprint><date when="2015">2015</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Background</italic>
. Novel rehabilitation strategies have demonstrated potential benefits for motor and non-motor symptoms of Parkinson's disease (PD).<italic> Objective</italic>
. To compare the effects of Lee Silverman Voice Therapy BIG (LSVT BIG therapy) versus a general exercise program (combined treadmill plus seated trunk and limb exercises) on motor and non-motor symptoms of PD.<italic> Methods</italic>
. Eleven patients with early-mid stage PD participated in the prospective, double-blinded, randomized clinical trial. Both groups received 16 one-hour supervised training sessions over 4 weeks. Outcome measures included the Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Modified Fatigue Impact Scale (MFIS). Five patients performed general exercise and six patients performed LSVT BIG therapy. Post-intervention evaluations were conducted at weeks 4, 12 and 24.<italic> Results</italic>
. The combined cohort made improvements at all follow-up evaluations with statistical significance for UPDRS total and motor, BDI, and MFIS (<italic>P</italic>
< 0.05).<italic> Conclusion</italic>
. This study demonstrated positive effects of general exercise and LSVT BIG therapy on motor and non-motor symptoms of patients with PD. Our results suggest that general exercise may be as effective as LSVT BIG therapy on symptoms of PD for patients not able to readily access outpatient LSVT BIG therapy.</p>
</div>
</front>
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<region><li>Californie</li>
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<name sortKey="Chen, Jack J" sort="Chen, Jack J" uniqKey="Chen J" first="Jack J." last="Chen">Jack J. Chen</name>
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